On 2 November 2022 the openGTN project held its Final Symposium. The meeting took place at partner University Medical Center Utrecht (UMCU) and was hosted by the Fall Meeting of the Dutch Society of Pattern Recognition and Image Processing (in Dutch: NVPHBV). A total of 100 persons registered. After a short introduction about openGTN by project coordinator prof. Marcel Breeuwer, keynote speaker prof. Sebastian Kozerke gave his view on the importance, status and potential of image simulation and synthesis. Thereafter, the 3 involved PhD researcher Sina Amirrajab, Aymen Ayaz and Yasmina Al Khalil presented their research achievements. All in all, a very successful meeting, with many interesting discussion during the breaks.